The effect of bicarbonate in increasing blood pressure in patients with hemorrhagic shock
Phase 2
Recruiting
- Conditions
- Condition 1: hemorrhagic shock. Condition 2: Acidosis.Hypovolemic shockAcidosisR57.1E87.2
- Registration Number
- IRCT20130304012695N5
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
All patients whose bleeding is more than 500 cc
systolic blood pressure lower than 100 mm
patients with ASA I,II,III who are candidates for orthopedic Hip surgery, neurosurgery, and vascular surgery.
patients required to receive blood transfusions,
patients with hemorrhagic shock
Exclusion Criteria
All patients with liver dysfunction
lung disorders such as COPD
increased ICP
Patients who do not agree to participate in this study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method actic Acidosis. Timepoint: At the end of surgery. Method of measurement: Vein blood sample mg/dl.;Blood pressure changes. Timepoint: After the start of bicarbonate or serum at minutes 3-6-9 12-15. Method of measurement: Through the artier line with Lidco device /mmgh.
- Secondary Outcome Measures
Name Time Method Blood acidosis. Timepoint: At the end of transfusion. Method of measurement: Arterial blood sample.