Effects of Paracetamol and Ibuprofen on wound healing in dental extraction patients.

Phase 4

Completed

• Conditions: Tooth extraction wound healing.; Surgery - Other surgery; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12624000595516
• Lead Sponsor: Residency Training Program in Oral and Maxillofacial, Surgery, Faculty of Dentistry, Chiang Mai University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2023-03-17
• Study Start: 2024-05-09
• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

For the inclusion criteria, subjects were selected as patients who need to remove upper third molar tooth within an age range of 15-30 years, who were of healthy status (American Society of Anesthesiologists: ASA class I and II), and who reported a normal body mass index (BMI) within a range of 18.5-24.5 kg/m2. In addition, they were free from pathological conditions, denied having any history of chronic illnesses and drug allergies.

Exclusion Criteria

The terms of exclusion were as follows: 1) Patients who were pregnant, heavy smokers, allergic to paracetamol, ibuprofen, or any anesthetic medications (e.g., mepivacaine and epinephrine-related drugs). 2) Patients who had undergone any pre-existing medical conditions such as hypertension, diabetes, liver disease, kidney disease, blood clotting disorders, and gastritis. 3) Patients who had wounds/injuries in various parts of their bodies prior to initiating the experimental study or those that had severe gingival inflammation (Gingival index > 2). 4). Patients who had taken medication or dietary supplements that could impact the wound healing process. 5) Patients who experienced psychological or communication disorders.

Study & Design

• Study Type: Interventional
• Study Design: Not specified