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临床试验/NCT07190950
NCT07190950招募中不适用

Effects of Low-level Laser Therapy on Soft and Hard Tissue Healing After Impacted Mandibular Third Molar Extraction

University of Medicine and Pharmacy at Ho Chi Minh City2 个研究点 分布在 1 个国家目标入组 22 人开始时间: 2024年8月30日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
22
试验地点
2
主要终点
wound healing score

研究概览

简要总结

Impacted lower third molar extraction is one of the most commonly performed dental procedures in daily practice. However, this is considered a relatively invasive procedure. During the surgery, dental surgeon must reflect a full-thickness flap, remove bone to expose the tooth, section and deliver the tooth. As a result, after surgery, patients often experience many complications, from swelling, pain, jaw tightness, etc. to alveolar bone loss, periodontal problems distal to the second molar, etc.

Therefore, clinicians are always looking for additional therapies to minimize complications, helping patients have a more comfortable experience after wisdom tooth surgery.

To date, placing grafting materials such as bone or other biological materials (growth factors, platelet-rich plasma, platelet-rich fibrin) into the tooth socket has been shown to be able to preserve the alveolar crest after extraction. However, these materials require preparation time, are costly, and have the risk of infection related to bone grafts.

Meanwhile, low-level laser therapy (LLLT) is known as a safe, non-invasive therapy that can affect cell metabolism without causing tissue damage. This therapy has been widely applied in many fields of medicine in general and in dentistry in particular. Low-level lasers have been studied to help reduce swelling, pain, and jaw tightness after impacted lower wisdom teeth surgery. In vitro or in vivo studies evaluating the healing effect of low-level lasers have given very positive results. However, there is still a lack of scientific evidence to prove the healing effect of low-level lasers on human tooth extraction sockets.

The study we conducted is a scientific study, in the field of Dentistry. This study aimed to evaluate the effectiveness of low-level laser on soft tissue and bone healing after surgical extraction of impacted lower third molars in a group of Vietnamese population.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy patients (at least 18 years of age) have both jaws lower impacted third molars indicated to be extracted. Both teeth are the same of

排除标准

  • 未提供

结局指标

主要结局

wound healing score

时间窗: at third, seventh and thirtieth day after third molar extraction surgery

Base on IPR scale (Inflammatory Proliferative Remodeling Scale) by Hamzani et al. (2018)

New bone density

时间窗: The day of surgery, first and third month after surgery

Based on periapical X-rays taken on the day of surgery right after extraction, first and third month, we calculate new bone density by calculate the pixel density at extracted socket.

Changing of alveolar crest level distal to second lower molar

时间窗: the day of surgery, first and third month after third molar extraction surgery

After taking periapical X-rays on the day of surgery right after extraction, first and third month, we measure alveolar crest level distal to second lower molar from the base of extracted socket to cemento-enamel junction (CEJ) of second molar (the reference is a 5 mm stainless steel straight wire buried in rubber impression)

次要结局

未报告次要终点

研究者

发起方
University of Medicine and Pharmacy at Ho Chi Minh City
申办方类型
Other
责任方
Principal Investigator
主要研究者

Nguyen Hoang Ngoc Hiep

DDS. Nguyen Hoang Ngoc Hiep

University of Medicine and Pharmacy at Ho Chi Minh City

研究点 (2)

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