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Bioequivalence Study for the Safety and the Pharmacokinetics of DWJ1567 in Healthy Adult Volunteers

Phase 1
Recruiting
Conditions
Healthy Volunteers
Interventions
Registration Number
NCT06109259
Lead Sponsor
Daewoong Pharmaceutical Co. LTD.
Brief Summary

This study aims to compare the pharmacokinetics and safety following administration of DWJ1567 and DWC202312 in healthy volunteers

Detailed Description

The study design is a Randomized, Open-label, Oral, Single-dose, Four-way crossover study. The patients were randomly assigned to each group. Primary endpoint was Cmax and AUCt of DWJ1567 and DWC202312. Secondary endpoints were AUCinf, Tmax, t1/2 of DWJ1567 and DWC202312.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
44
Inclusion Criteria
  • Over 19 year old
Exclusion Criteria
  • Galactose intolerance
  • Lapp lactase deficiency

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
DWC202312DWC202312DWC202312
DWJ1567DWJ1567DWJ1567
Primary Outcome Measures
NameTimeMethod
Cmax,ss of DWJ1567 and DWC202312At pre-dose (0 hour), and post-dose 0 to 72 hour.
AUCt of DWJ1567 and DWC202312At pre-dose (0 hour), and post-dose 0 to 72 hour.
Secondary Outcome Measures
NameTimeMethod
AUCt/AUCinf of DWJ1567 and DWC202312At pre-dose (0 hour), and post-dose 0 to 72 hour
AUCinf of DWJ1567 and DWC202312At pre-dose (0 hour), and post-dose 0 to 72 hour
Tmax of DWJ1567 and DWC202312At pre-dose (0 hour), and post-dose 0 to 72 hour
t1/2 of DWJ1567 and DWC202312At pre-dose (0 hour), and post-dose 0 to 72 hour

Trial Locations

Locations (1)

H Plus YANGJI Hospital

🇰🇷

Seoul, Korea, Republic of

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