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Bioequivalence Study for the Safety and the Pharmacokinetics of DWJ1568 in Healthy Adult Volunteers

Phase 1
Recruiting
Conditions
Healthy Volunteers
Interventions
Registration Number
NCT06119945
Lead Sponsor
Daewoong Pharmaceutical Co. LTD.
Brief Summary

This study aims to compare the pharmacokinetics and safety following administration of DWJ1568 and DWC202215 in healthy volunteers

Detailed Description

The study design is a Randomized, Open-label, Oral, Single-dose, Four-way crossover study. The patients were randomly assigned to each group. Primary endpoint was Cmax and AUCt of DWJ1568 and DWC202215. Secondary endpoints were AUCinf, Tmax, t1/2 of DWJ1568 and DWC202215.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
44
Inclusion Criteria
  • over 19 year old
Exclusion Criteria
  • Galactose intolerance
  • Lapp lactase deficiency

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
DWJ1568DWJ1568DWJ1568
DWC202215DWC202215DWC202215
Primary Outcome Measures
NameTimeMethod
Cmax,ss of DWJ1568 and DWC202215At pre-dose (0 hour), and post-dose 0 to 72 hour.
AUCt of DWJ1568 and DWC202215At pre-dose (0 hour), and post-dose 0 to 72 hour.
Secondary Outcome Measures
NameTimeMethod
t1/2 of DWJ1568 and DWC202215At pre-dose (0 hour), and post-dose 0 to 72 hour.
AUCinf of DWJ1568 and DWC202215At pre-dose (0 hour), and post-dose 0 to 72 hour.
Tmax of DWJ1568 and DWC202215At pre-dose (0 hour), and post-dose 0 to 72 hour.
AUCt/AUCinf of DWJ1568 and DWC202215At pre-dose (0 hour), and post-dose 0 to 72 hour.

Trial Locations

Locations (1)

H Plus YANGJI Hospital

🇰🇷

Seoul, Korea, Republic of

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