Impact of l-carnitine in percutaneous coronary interventio
Not Applicable
- Conditions
- ischemic heart disease.I20-I25Myocardial ischemia followed by decreased oxygen to the myocardium
- Registration Number
- IRCT201212178698N4
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Patients with ischemic heart disease that have more than 50 percent occlusion in angiography findings and candidates for elective Pecrcutaneous Coronary Intevention.Exclusion criteria: cardiogenic shock;ST Elevation Myocardial Infarction;pregnant and lactating womens;patients under 18 years;immunologic or hematologic disorders;current infection;chronic kidney disease;serum creatinine above 2.5 mg/dl;hypothyroidism;epilepsy or convulsion;chronic liver disease;cancer
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Transforming growth factor beta(TGF-ß). Timepoint: baseline and 24 hour after. Method of measurement: Elisa kit.;CD40L. Timepoint: baseline and 24 hour after. Method of measurement: Elisa kit.;P-Selectin. Timepoint: baseline and 24 hour after. Method of measurement: Elisa kit.
- Secondary Outcome Measures
Name Time Method Major adverse cardiac events)MACE). Timepoint: 1 month later. Method of measurement: evaluation of patient condition such as death, stent thrombosis confirmed by angiography ? acute coronary syndrome defined by AHA ? again revascularization with angioplasty or bypass.