Evaluating the effect of L-carnitine on the prevention of postoperative atrial fibrillation and acute kidney injury (AKI) following coronery artery bypass grafting (CABG) surgery.
Not Applicable
- Conditions
- ischemic heart disease.Atherosclerotic heart disease
- Registration Number
- IRCT201301028698N7
- Lead Sponsor
- Tehran university of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
] The patients who candidate for Coronary artery bypass graft surgery in Tehran Heart center are selected by simple randomised method; There are not any limitations for age; and sex in this study. Exclusion criteria: Valvular surgery; History of supraventricular arrhythmia; History of siezure; History of hypersensitivity reaction to l-carnitine; Chronic liver failure (Liver enzymes more than 3 times of ULN); Chronic kidney disease (Stage IV & V); Hypothyroidism; Use of Magnesium, NSAIDs and Antiarrhythmic medication.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Atrial fibrillation. Timepoint: 5 days post CABG surgery. Method of measurement: ECG, hs-CRP.
- Secondary Outcome Measures
Name Time Method Acute kidney injury. Timepoint: up to 48 hours after surgery. Method of measurement: NGAL, serum creatinine.