Assessment and Hemodynamic Response in CABG After Cardiopulmonary Bypass Using Intraoperative Transesophegeal Echocardiography
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 81
- 试验地点
- 1
- 主要终点
- Systolic and diastolic heart function
研究概览
简要总结
This is a double blind randomization study, assessing hemodynamic response in patients who underwent a cardiopulmonary bypass graft (CABG) with cardiopulmonary bypass (CPB) using intraoperative trasnesophageal echocardiography (TEE) to know what inotropic drug will be batter to improve the heart function. Epinephrine, milrinone, dobutamine and levosimendan will be assessment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 45 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Sinusal ritmus
- •EF > 35%
- •Elective CABG surgery
排除标准
- •No accept
- •Severe valvular regurgitation or stenoses
- •Chest pain
- •Cardiogenic shock
研究组 & 干预措施
epinephrine
Assessment of systolic and diastolic heart function during CABAG with CPB with levosimendan using TEE.
干预措施: epinephrine and levosimendan (Drug)
levosimendan
Assessment of systolic and diastolic heart function during CABAG with CPB with epinephrine using TEE.
干预措施: epinephrine and levosimendan (Drug)
结局指标
主要结局
Systolic and diastolic heart function
时间窗: Two years
Assessment the systolic and diastolic heart function
次要结局
- Mortality after CABAG(Two years)
研究者
Marcello F Salgado Filho, MD
Principal investigator
Universidade Federal do Rio de Janeiro