willow bark and dysmenorrhea
Phase 3
- Conditions
- primary dysmenorrhea.
- Registration Number
- IRCT20180123038486N1
- Lead Sponsor
- Shahre-kord University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 110
Inclusion Criteria
suffering from level two or three primary dysmenorrhea according to the Andersch and Milsom’s verbal multi-dimensional scoring system
aged 18 to 28 years old
regular menstrual cycles
without history of allergy to willow bark
single students
Exclusion Criteria
absence of any genital organs diseases
history of hypersensitivity to NSAIDs
systemic diseases
neurologic or psychiatric disease
surgery during the past eight weeks
hormonal therapy during the last six months
used contraceptives
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain level. Timepoint: Before intervention and After Intervention. Method of measurement: visual analog scale (VAS).;Menstrual symptoms. Timepoint: Before intervention and After Intervention. Method of measurement: COX menstrual symptom scale.;Bleeding amount. Timepoint: Before intervention and After Intervention. Method of measurement: Pictorial blood assessment chart.
- Secondary Outcome Measures
Name Time Method Safety and adverse event. Timepoint: After intervention. Method of measurement: case-report form.