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The effect of licorice syrup on dysmenorrhea

Phase 3
Conditions
Primary dysmenorrhea.
Primary dysmenorrhea
Registration Number
IRCT2015081323610N1
Lead Sponsor
Vice Chancellor for research, Shahid Sadoughei University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Female
Target Recruitment
60
Inclusion Criteria

Inclusion Criteria: Aged between 18-25 years; Moderate and severe dysmenorrhea (grade 2, 3) based on Verbal Multidimensional Scoring System; Regular menstrual cycles (every 21-35 days and bleeding 3 to 10 days for at least three recent cycles).
Exclusion criteria: Pelvic pathology (including Endometriosis, Adenomyosis, Fibroids, Ovarian Cysts, Pelvic Inflammatory Disease, etc); Known diseases (including Chronic Hepatitis, Cholestatic Liver Disease, Cirrhosis, Severe Renal Insufficiency, Diabetes Mellitus, Arrhythmias, Hypertension, Hypertonia and Hypokalemia); Existence of stressors (such as loss of a close relative and Intense familial debate) during recent 6 months; History of allergy to licorice; Concurrent use of other products containing licorice; Taking another painkiller that is not defined in the study; Concomitant use of OCP; Drug intolerance; Lack of desire to continue the treatment for any reason; Another disease that will have required medical treatment during the study.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Pain intensity. Timepoint: Before intervention- Every day during intervention. Method of measurement: Visual Analogue Scale(VAS).;Pain duration. Timepoint: Before intervention- Every day during intervention. Method of measurement: hour.
Secondary Outcome Measures
NameTimeMethod
Adverse effect of licorice syrup. Timepoint: At the end of each cycle of intervention. Method of measurement: Questionnaire.;Adverse effect of Ibuprofen such as Nausea, dyspepsia, vomiting, ulcers and gastrointestinal bleeding. Timepoint: At the end of each cycle of intervention. Method of measurement: Questionnaire.
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