跳至主要内容
临床试验/NCT00728273
NCT00728273已完成2 期

Efficacy of Multiple Micronutrient Fortified Biscuits and Deworming on Reducing Anemia Prevalence, and Improving Micronutrient Status, Cognitive Function, and Growth in Vietnamese School Children

Neys-van Hoogstraten Foundation, The Netherlands2 个研究点 分布在 1 个国家目标入组 510 人开始时间: 2007年1月1日最近更新:
适应症

试验速览

阶段
2 期
状态
已完成
发起方
入组人数
510
试验地点
2
主要终点
Prevalence of anemia, micronutrient status (iron, vitamin A, zinc, and iodine), and cognitive function (attention, IQ, concentration, and school achievement).

研究概览

简要总结

The aim of this study is to identify the effect of a school-based food fortification intervention with multi-micronutrients with or without deworming to improve anemia, micronutrient status, cognitive function, health (morbidity and reinfestation rate) and growth (ponderal) in Vietnamese primary schoolchildren.

详细描述

Concurrent micronutrient deficiencies are prevalent in schoolchildren in Vietnam. These deficiencies not only lead to anemia, impair growth, increase susceptibility to infection, impair work capacity, but also impair cognitive development and impair learning ability. The risk of micronutrient deficiencies and anemia increases when individuals are exposed to intestinal helminth infections. Schoolchildren are a neglected group with regard to micronutrient interventions, and school programs afford an excellent opportunity to improve health of these groups. Food fortification with multi-micronutrients is a cost-effective and sustainable strategy, but is not yet implemented on a large scale in Vietnam. Furthermore, little is known about whether high prevalence of intestinal helminthic infection in schoolchildren limits the effect of fortification when this is not combined with regular de-worming.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Basic Science
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
6 Years 至 8 Years(Child)
性别
All
接受健康志愿者

入选标准

  • school children aged 6-8 years with written informed consent from parents/caregivers

排除标准

  • hemoglobin concentrations < 80g/L
  • chronic disease
  • congenital abnormalities
  • mental or severe physical handicap
  • severe malnutrition
  • receiving deworming within the previous 6 mo

结局指标

主要结局

Prevalence of anemia, micronutrient status (iron, vitamin A, zinc, and iodine), and cognitive function (attention, IQ, concentration, and school achievement).

时间窗: 4 months

次要结局

  • prevalence and incidence of infectious diseases such as diarrhea and respiratory infection over a 4-month period during the school feeding in(4 months)
  • growth (especially weight), body composition (body fat)(4 months)

研究者

发起方
Neys-van Hoogstraten Foundation, The Netherlands
申办方类型
Other

研究点 (2)

Loading locations...

相似试验

Efficacy of Multiple Micronutrient Fortified... | 临床试验