Het natuurlijk beloop van inflammatoire darmziekten tijdens de zwangerschap
Recruiting
- Conditions
- Inflammatory bowel diseasePregnancyGut microbiome
- Registration Number
- NL-OMON28895
- Lead Sponsor
- Erasmus Universit Medical Centre Rotterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 270
Inclusion Criteria
Female
- Age 18-43
Exclusion Criteria
- Incapacity to understand pre-conceptional counseling, informed consent and/or questionnaire (e.g. language barrier, no interpreter)
- Diabetes mellitus
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - to analyze the gut microbiome of IBD patients during pregnancy; can the changes during pregnancy in the gut microbiome be linked to disease activity/flares.
- Secondary Outcome Measures
Name Time Method - to analyze the effect of disease activity on pregnancy outcomes (gestational term, birth weight, congenital abnormalities, mode of delivery) <br /><br>- to identify risk factors for an adverse disease course during pregnancy and adverse pregnancy outcomes<br /><br>- to analyze the effect of different IBD medication use, independent of disease activity, during pregnancy on pregnancy course and outcomes<br /><br>- to obtain data on the health of children born to IBD mothers (infections, allergies, growth) until 1 year and compare to children born to healthy mothers<br>