After Surgery Acute Renal Failure Incidence in Total Knee Arthroplasty With and Without Tourniquet

Not Applicable

Completed

• Conditions: Acute Kidney Injury; Knee Osteoarthritis; Arthroplasty, Replacement, Knee; Tourniquets
• Interventions: Procedure: total knee arthroplasty; Procedure: Tourniquet limb cuff; Drug: Intaarticular lidocain

• Registration Number: NCT03795805
• Lead Sponsor: Instituto Mexicano del Seguro Social

Brief Summary

This study analize the incidence of acute renal failure after performing total knee arthroplasty with or without use of tourniquet limb cuff (half of patients for each group) in a randomized clinical trial

Detailed Description

This study analize the incidence of acute renal failure after performing total knee arthroplasty with or without (using local intraarticular anesthesia) use of tourniquet limb cuff (half of patients for each group) in a randomized clinical trial

Study Timeline

• Study Start: 2018-03-15
• Primary Completion: 2018-11-20
• Study Completion: 2018-12-20
• Study First Submitted: 2018-12-26
• Status Verified: 2019-01
• Study First Submitted QC: 2019-01-07
• Last Update Submitted: 2019-01-07
• Study First Posted: 2019-01-08
• Last Update Posted: 2019-01-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Patients knee arthrosis
• Required a surgical treatment with Total Knee Arthroplasty

Exclusion Criteria

• Not accept to be in the study
• Not signed consent form
• Not having blood sample for creatinin meassure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
TKA and Tourniquet	total knee arthroplasty	Total knee arthroplasty and use of tourniquet limb cuff at 270 mmHg
TKA and Tourniquet	Tourniquet limb cuff	Total knee arthroplasty and use of tourniquet limb cuff at 270 mmHg
Intraarticular lidocain	total knee arthroplasty	Total knee arthroplasty with Intaarticular lidocain
Intraarticular lidocain	Intaarticular lidocain	Total knee arthroplasty with Intaarticular lidocain

Primary Outcome Measures

Name	Time	Method
Creatinin after surgery 1	Creatinin after surgery 1 at 24 hours	Blood Creatinin meassure in mg/dl at 24 hours
Creatinin after surgery 2	Creatinin after surgery 2 at 48 hours	Blood Creatinin meassure in mg/dl at 48 hours
Creatinin before surgery	Creatinin before surgery	Blood Creatinin meassure in mg/dl before surgery

Trial Locations

Locations (1)

UMAE Dr. Victorio de La Fuente Narvaez; 🇲🇽 Ciudad de México, Mexico