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Clinical Trials/NCT03795805
NCT03795805
Completed
Not Applicable

After Surgery Acute Renal Failure Incidence in Total Knee Arthroplasty With and Without Tourniquet

Instituto Mexicano del Seguro Social1 site in 1 country100 target enrollmentMarch 15, 2018

Overview

Phase
Not Applicable
Intervention
total knee arthroplasty
Conditions
Arthroplasty, Replacement, Knee
Sponsor
Instituto Mexicano del Seguro Social
Enrollment
100
Locations
1
Primary Endpoint
Creatinin after surgery 1
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

This study analize the incidence of acute renal failure after performing total knee arthroplasty with or without use of tourniquet limb cuff (half of patients for each group) in a randomized clinical trial

Detailed Description

This study analize the incidence of acute renal failure after performing total knee arthroplasty with or without (using local intraarticular anesthesia) use of tourniquet limb cuff (half of patients for each group) in a randomized clinical trial

Registry
clinicaltrials.gov
Start Date
March 15, 2018
End Date
December 20, 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

JUAN LOPEZ VALENCIA

Principal Investigator

Instituto Mexicano del Seguro Social

Eligibility Criteria

Inclusion Criteria

  • Patients knee arthrosis
  • Required a surgical treatment with Total Knee Arthroplasty

Exclusion Criteria

  • Not accept to be in the study
  • Not signed consent form
  • Not having blood sample for creatinin meassure

Arms & Interventions

TKA and Tourniquet

Total knee arthroplasty and use of tourniquet limb cuff at 270 mmHg

Intervention: total knee arthroplasty

TKA and Tourniquet

Total knee arthroplasty and use of tourniquet limb cuff at 270 mmHg

Intervention: Tourniquet limb cuff

Intraarticular lidocain

Total knee arthroplasty with Intaarticular lidocain

Intervention: total knee arthroplasty

Intraarticular lidocain

Total knee arthroplasty with Intaarticular lidocain

Intervention: Intaarticular lidocain

Outcomes

Primary Outcomes

Creatinin after surgery 1

Time Frame: Creatinin after surgery 1 at 24 hours

Blood Creatinin meassure in mg/dl at 24 hours

Creatinin after surgery 2

Time Frame: Creatinin after surgery 2 at 48 hours

Blood Creatinin meassure in mg/dl at 48 hours

Creatinin before surgery

Time Frame: Creatinin before surgery

Blood Creatinin meassure in mg/dl before surgery

Study Sites (1)

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