跳至主要内容
临床试验/CTRI/2025/01/079536
CTRI/2025/01/079536尚未招募3 期

A Comparative Clinical Study to evaluate the efficacy of Patoladi Kwatha and Phalatrikadi Kwatha in management of Bahupitta Kamala.

Dr. Vijaya Pandurang Dhumal1 个研究点 分布在 1 个国家目标入组 72 人开始时间: 2025年2月6日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
72
试验地点
1
主要终点
LFTs

研究概览

简要总结

Jaundice is a condition in which yellowish discoloration appears on the skin, in mucous

membrane and sclera due to elevated levels of bilirubin in the bloodstream. Jaundice

frequently indicate problem with liver functioning.

At Present scenario, industrialization has brought a lot of changes in our lifestyle and

especially in food eating habits. Most of the people have become used to spicy fast-food day

by day. This changes in lifestyle has invited various diseases. Also there is increased

prevalence due to increased population living in congested area, poor sanitation and

consumption of unhygienic food and polluted water, etc.

Modern science has limitations in treating Kamala Vyadhi (jaundice) but Ayurvedic

literature clearly explained pathology and treatment of Kamala Vyadhi which shows the

specificity of Ayurveda.

Modern system of medicine is basically designed to alleviate the symptoms, on other

hand Ayurveda based upon upon mind, body soul theory and make use of natural products

with fewer side effects and is targeted to eliminate root cause by establishing balance in body

physiology.

Patoladi Kwatha 4 is an Ayurvedic herbal formulation that is used in Kamala. The

rationale behind its potential efficacy lies in the specific properties of the herbs used in its

preparation and their traditional use in Ayurveda for liver-related disorders.

The key ingredients in Patoladi Kwatha include :-

Trichosanthes dioicia

(Patola)

Picrorhiza kurroa (Katurohini)

Tinospora cordifolia (Guduchi)

Santalum album (Chandana)

Marsdenia tenacissima (Murva)

Cissampelos parieria (Patha).

These herbs are believed to possess hepatoprotective, antioxidant, anti-inflammatory, and

immunomodulatory properties, which could potentially aid in the treatment of jaundice.5

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
19.00 Year(s) 至 60.00 Year(s)(—)

入选标准

  • Age limit is from 19 to 60 years irrespective of Gender, Occupation, Religion and Economical condition.
  • Patients having raised serum bilirubin 1.5-15 mg/dl
  • Having signs and symptoms of Bahupitta Kamala with cardinal symptoms :-
  • Haridra Netra
  • Haridra Twaka
  • Rakta peeta mutrata associated symptoms:-
  • Dourbalya
  • Anutsaha 5.

排除标准

  • Known cases of HIV infection, Malignancy
  • Patients in hepatic encephalopathy.
  • Pregnant & lactating mother
  • Psychotic patients
  • Congenital Causes -Gilbert’s Syndrome
  • Drug induced hyper bilirubinaemia.

结局指标

主要结局

LFTs

时间窗: Baseline 15th day,30th day,45th day

To compare the efficacy of Patoladi Kwatha and Phalatrikadi Kwatha in Bahupitta Kamala

时间窗: Baseline 15th day,30th day,45th day

次要结局

  • To observe adverse effects of Patoladi Kwatha and Phalatrikadi Kwatha(At base line,15th day,30th day,45th day)

研究者

发起方
Dr. Vijaya Pandurang Dhumal
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Vijaya Pandurang Dhumal

MAMs Sumatibhai Shah Ayurved Mahavidyalaya Malwadi Hadapsar Pune

研究点 (1)

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