A randomized controlled phase III study comparing circular stapler vs modified Collard technique as esophagogastric anastomosis after esophagectomy for thoracic esophageal cancer
Phase 3
- Conditions
- Thoracic esophageal cancer
- Registration Number
- JPRN-UMIN000029561
- Lead Sponsor
- Aichi Cancer Center Hospital Department of Gastroenterological Surgery
- Brief Summary
Among 100 randomized patients (CS group, n =50; MC group, n =50), anastomotic strictures were observed in 18 (42%) patients in the CS group and in no patients in the MC group. There were no significant between-group differences in anastomotic leakage (CS group, 7% vs MC group, 8%; P =0.94). Quality of life domains of dysphagia and choking when swallowing at 3 months after surgery were significantly better in the MC group than in the CS group.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1)Salvage surgery 2)Patients performed preoperative chemoradiotherapy 3)severe complications 4)Patients judged inappropriate for the study by the physicians
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of anastomotic stricture
- Secondary Outcome Measures
Name Time Method Incidence of anastomotic leakage Incidence of postoperative complication Time of anastomosis QO