The use of End Expiratory Occlusion Test vs. Inferior Vena Cava Respiratory Variation for prediction of volume responsiveness in mechanically ventilated patients with sepsis
- Conditions
- Assessment of fluid responsiveness in septic shock patients
- Registration Number
- PACTR202306581320725
- Lead Sponsor
- Faculty of medicine Ain Shams university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 34
age 21-60 years old
both sexes
Septic hypotensive patients
sedated intubated on controlled mechanical ventilation with no respiratory effort.
in need of intravenous fluid administration for resuscitation according to the clinical presentation (systolic arterial blood pressure (BP) < 90 mmHg, or mean arterial pressure (MAP) < 65 mmHg, or a fall of > 20 mmHg from the baseline of MAP, or with signs of hypoperfusion including oliguria less than 0.5 ml/kg/h and arterial lactate > 2.5 mmol/L).
Spontaneous breathing
poor cardiac echogenicity
cardiac arrhythmia
Severe valvular heart disease / intracardiac shunt
impaired left ventricular function with ejection fraction < 40%
ascites
pregnancy
malignancy
congestive heart failure
Evidence of fluid over-load
renal dysfunction.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method