Comparison the effect of 3 day with 7 day GNRH-antagonist in prevention of ovarian hyperstimulation syndrome(OHSS)

Phase 2

Recruiting

• Conditions: Ovarian hyperstimulation syndrome.; Hyperstimulation of ovaries; N98.1

• Registration Number: IRCT20201126049497N1
• Lead Sponsor: Birjand University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 November 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

Having informed consent to enter the study.
The possibility of useful intervention on individuals.
Age between 18 and 40 years.
The person is at risk for OHSS syndrome (for example, the number of recovered eggs is more than 15 or serum estradiol more than 3000 pg / ml
Any person who does not meet any of the exclusion criteria will be included in the study if satisfied

Exclusion Criteria

Dissatisfaction to enter the study
Age less than 18 years or more than 40 years
Any disease that interferes with the intended intervention.
Patient with diabetes / hemophilia or coagulation disorde
Patients with pulmonary fibrosis, swelling or inflammation around the heart or lungs, high blood pressure, liver disease, heart valve disease, or allergy to cabergoline or ergot derivatives
Use of drugs that affect the development of OHSS syndrome (calcium gluconate / metformin / letrozole / other GNRH-ant antagonists)
Pregnancy during the study cycle
Contraindications that are considered by a specialist and are not included in the test.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Ovarian hyperstimulation syndrome. Timepoint: One week after OPU. Method of measurement: Clinical and laboratory evaluation and sonography.