Effect of delayed start protocol in outcome of ART cycle in poor ovarian responders
Phase 2
- Conditions
- Infertility.Complication associated with artificial fertilization, unspecifiedN98.9
- Registration Number
- IRCT2015100424335N1
- Lead Sponsor
- Vice Chancellor for research of Shahid Sadoughi University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 72
Inclusion Criteria
Poor ovarian responders according to Bologna criteria. At least two of the following three features must be present:
Advanced maternal age (=40 years) or any other risk factor for poor ovarian response;
A previous poor ovarian response (=3 oocytes with a conventional stimulation protocol);
An abnormal ovarian reserve test (i.e. AFC <5–7 follicles or AMH <1.1 ng/ml).
Two episodes of POR after maximal stimulation are sufficient to define a patient as poor responder.
Exclusion Criteria
History of endocrine and metabolic disorders
endometriosis
azoospermia
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mature oocytes count. Timepoint: Oocyte retrieval day. Method of measurement: Counting number of mature oocytes with microscope.;Total oocytes count. Timepoint: Oocyte retrieval day. Method of measurement: Counting number of total oocytes with microscope.
- Secondary Outcome Measures
Name Time Method