Early initiation of GnRH Antagonist in Poor responder Patients

Phase 3

Recruiting

• Conditions: Poor Ovarian Response.; Complications associated with artificial fertilization

• Registration Number: IRCT20110731007165N9
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 February 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 116

Inclusion Criteria

Age between 18 up to 44 years
History of poor ovarian response (POR) in previous cycle (oocyte less than 3 in a conventional protocol)
Antral follicle count (AFC) less than 5-7 or Anti-Müllerian hormone (AMH) <0.5-1.1
Poor ovarian response after maximal stimulation

Exclusion Criteria

Polycystic Ovarian Syndrome
Hypothalamic amenorrhea
Uterine congenital anomalies and uterine cavity abnormalities (Bicorn uterus, Unicorn uterus, Asherman, Liomyuma, Polyp, etc.)
Repeated IVF failure (more than three consecutive failures)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
umber of Mature Retrieved Oocytes. Timepoint: At the end of the study. Method of measurement: Embryology Report.;Embryos. Timepoint: At the end of the study. Method of measurement: Embryology Report.;Total Gonadotropins used. Timepoint: At the end of the study. Method of measurement: Checklist.;Total Antagonist used. Timepoint: At the end of the study. Method of measurement: Checklist.;Total Days of Induction of ovulation. Timepoint: At the end of the study. Method of measurement: Checklist.;Total Number of Retrieved Oocytes. Timepoint: At the end of the study. Method of measurement: Embryology Report.