Using the Deep Temporal Nerves Versus the Masseteric Nerve for Correction of Eyelid Paresis Caused by Facial Nerve Affection. A Comparative Clinical Study.
试验速览
- 阶段
- 不适用
- 入组人数
- 24
- 主要终点
- Palpebral fissure size
研究概览
简要总结
The return of eyelid function and facial expression in Patients with facial nerve affection is very important for quality of life. Eyelid dysfunction leads to drying and ulceration of cornea which may lead to permanent vision loss.
Facial paralysis is distinguished into two main groups according to the presence or absence of facial fibrillations at needle Electromyography. Recent paralysis, mainly lasting less than two years generally show these signs and are eligible for reactivation of facial nerve by anastomosing it to a donor one (early facial reanimation).
The masseteric nerve (motor branch of trigeminal nerve ) is a reliable donor nerve on early facial reanimation.
The deep temporal nerves are motor branches of trigeminal nerve which have some advantage over masseteric nerve as they are longer and reach the zygomatic and frontal branch of facial nerve and it can reach the eyelid and eyebrow to be used for direct neurotization and it supplies temporalis muscle which is an expandable muscle with little effect on mastication and it was reported that they can restore blinking.
So on this study we examine the advantages and disadvantages of both nerves to develop a protocol for use of both especially on eyelid reanimation and restoration of blinking on upper facial segment paresis
详细描述
Type of the study: Prospective Interventional Study (clinical trial)
Intervention Model Description:
Patients will be randomized into two groups according to the surgical procedure performed as follows:
- Group A: Deep temporal nerves.
- Group B: Masseteric nerve.
Allocation and Randomization:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Facial nerve paresis with upper eyelid affection.
- •Patients are generally fit with no other disease interfere with microsurgery. 3.Electromyography of eyelid showing fibrillations.
排除标准
- •Patient with other medical or mental disease causing generalized paralysis.
- •Syndromic cases.
- •Patients are generally unfit or with any disease interfere with microsurgery.
- •Electromyography of eyelid showing no fibrillations.
结局指标
主要结局
Palpebral fissure size
时间窗: 6 months after surgery
Comparing the outcomes on palpebral fissure size between the deep temporal group and the masseteric group after 6 months from the surgery.
次要结局
未报告次要终点
研究者
Ahmed Mohamed Refaat Ahmed Abdelkarim
Principal Investigator
Assiut University
