Sound Acupuncture in Painful Chemotherapy-Related Neuropathies

Not Applicable

Completed

• Conditions: Neuropathic Pain in Cancer

• Registration Number: NCT07187986
• Lead Sponsor: Ente Ospedaliero Ospedali Galliera

Brief Summary

The objective of this clinical trial is to evaluate the efficacy of sound acupuncture in combination with traditional medical therapy in the treatment of chemotherapy-induced peripheral neuropathies.

Sound acupuncture is a non-invasive technique that involves stimulating energy points, used in acupuncture, with the help of specific tuning forks and the frequencies they emit.

The energy points are those used in Chinese medicine and, more specifically, in acupuncture.

The aim is to restore the recipient's complex bioenergetic system to an optimal state of well-being and balance

Participants:

20 patients will receive only the best medical therapy; 20 patients will receive BMT and sound acupuncture treatment

Detailed Description

Not available

Study Timeline

• Study Start: 2022-03-17
• Primary Completion: 2025-07-15
• Study Completion: 2025-07-16
• Study First Submitted: 2025-08-04
• Status Verified: 2025-09
• Study First Submitted QC: 2025-09-16
• Last Update Submitted: 2025-09-16
• Study First Posted: 2025-09-23
• Last Update Posted: 2025-09-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Age 30-80 years
• Clinical and electrophysiological diagnosis of chemotherapy-induced neuropathy
• Patients being treated with Best Medical Therapy for neuropathic pain
• Written informed consent

Exclusion Criteria

• Women who are pregnant or breastfeeding
• Patients with intellectual disabilities or cognitive impairment that impair their ability to comply with the consent process
• Pacemaker users

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Pain reduction	1 year	At least a 30% reduction from baseline on the NPS scale for neuropathic pain

Secondary Outcome Measures

Name	Time	Method
Back Depression inventory	1 year	Effectiveness of sound therapy combined with pharmacological treatment through administration of the BDI-II scale
Quality of life assessment	1 year	EQ-5D scale for assessing the impact on quality of life

Trial Locations

Locations (1)

E.O. Ospedali Galliera; 🇮🇹 Genoa, Liguria, Italy