Comparison of treatment outcomes between endoscopic injection of new agent of Vantris® and open surgery of Gil-vernet in 1-10 year-aged children with primary vesicoureteral reflux

Not Applicable

• Conditions: Vesicouretral reflux.; Congenital vesico-uretero-renal reflux

• Registration Number: IRCT2015022321211N1
• Lead Sponsor: Vice Chancellor Of Research Of Tabriz University Of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Iinclusion criteriae: 1)1-10 years of old ; 2) II to IV grade VURs, as defined below: a) Symptomatic UTIs(such as fever,dysuria,poor feeding, FTT); New renal scarring despite of antibiotic prophylaxis; bilateral VUR; Intolerance to prophylactic antibiotics; parent tendency to surgical repair. Exclusion criteriae: 1)Grades I and V ; 2) previously open or endoscopic surgeries on bladder or ureters ; 3) Anantomic malformations of urinary tract such as obstructive disorders or complete duplication of pyelocaliceal system ; 4)suspicion to or confirmed voiding disorder : a. presence of related clinical findings including abnormal neurologic exam or elimination disorder(instinal and urinary, with together); b.VCUG or ultrasonographic abnormalities such as bladder wall abnormalities or diverticuli ortrabeculation or decreased vesical capacity ; 5)Neurogenic bladder

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Grade of VUR. Timepoint: 3 months. Method of measurement: Grading system for VUR on VCUG, )International Reflux Study Committee ).

Secondary Outcome Measures

Name	Time	Method
nimproved VUR. Timepoint: 3 months. Method of measurement: Grading system for VUR on VCUG, )International Reflux Study Committee ).