Corneal Endothelium After Phacoemulsification in Pseudo Exfoliation Syndrome
- Conditions
- Corneal Endothelial Cell LossPseudoexfoliation Syndrome
- Interventions
- Procedure: phacoemulsification
- Registration Number
- NCT05447130
- Lead Sponsor
- Minia University
- Brief Summary
To study corneal endothelial cells changes after phacoemulsification in patients with senile cataract and pseudoexfoliation syndrome (PEX) compared with control patients with senile cataract using specular microscope.
- Detailed Description
In a prospective interventional case-control study, 20 eyes with cataract and PEX and 20 control eyes with cataract without PXE were subjected to phacoemulsification and posterior chamber foldable intraocular lens implantation in Minia University Hospital and Genaidy Eye Center between March 2019 and December 2020. Specular microscopy was done preoperatively, 3 and 6 months postoperatively. Endothelium cell density (ECD), coefficient variation (CV), hexagonality, pleomorphism and corneal thickness were evaluated and compares between PXE and control eyes.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
- senile cataract age more than 55 years
- PEX with glaucoma, eyes with cornea guttata or any corneal dystrophy, zonular dehiscence, very dense nuclear cataract (cataracta nigra) history of previous ocular surgery.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Corneal Endothelial Evaluation after Phacoemulsification in Eyes with Pseudoexfoliation Syndrome phacoemulsification - Corneal Endothelial Evaluation after Phacoemulsification in Eyes without Pseudoexfoliation phacoemulsification -
- Primary Outcome Measures
Name Time Method corneal endothelial cell loss 6 months corneal endothelial cell loss
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Minia University Hospital
🇪🇬Minya, Minia, Egypt