Paramedic acute stroke treatment assessment (PASTA)

Not Applicable

Completed

• Conditions: Topic: Stroke; Subtopic: Acute Care; Disease: In hospital study, Community study; Nervous System Diseases; Stroke

• Registration Number: ISRCTN12418919
• Lead Sponsor: ewcastle upon Tyne Hospitals NHS Foundation Trust

Brief Summary

2019 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/30755249 protocol 2020 Results article in https://pubmed.ncbi.nlm.nih.gov/32282015 results (added 15/04/2020) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33724103/ economic results (added 17/03/2021) 2019 Abstract results in https://doi.org/10.1177/2396987319845560 (added 30/11/2022) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35637776/ (added 30/11/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-11-05
• Study Completion: 2019-04-30
• Last Update Posted: 9 January 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1214

Inclusion Criteria

Paramedics allocated to delivering the PASTA pathway will be asked to deliver this to the following patients:
1. Aged 18 years and over.
2. Face Arm Speech Test (FAST) positive or any presentation of new focal neurological symptoms which indicate acute stroke in the paramedic's clinical judgement.
3. Within 4 hours of last known to be without new stroke symptoms in the paramedic’s judgement.
4. Admission to a study hospital

Patients will be identified and approached about enrolment in the study after arrival at hospital. Patients approached about enrolment will meet the following criteria:
1. Travelled to hospital with a study paramedic
2. Aged 18 years and over
3. Hospital specialist diagnosis of stroke
4. Within 4 hours of stroke onset (onset time determined by the hospital stroke team) when assessed by the study paramedic

Exclusion Criteria

Not meeting the inclusion criteria

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Current primary outcome measure as of 18/12/2019:<br> Treatment with intravenous thrombolysis on the day of hospital admission assessed by examining medical records<br><br> Previous primary outcome measure:<br> Dependency measured using the modified Rankin Scale (mRS) at 90 days after stroke.<br>