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Clinical Trials/NCT07547124
NCT07547124
Not yet recruiting
Not Applicable

Association Between Postoperative Analgesic Approaches and Quality of Recovery and Swallowing Pain in Patients Undergoing Elective Total Thyroidectomy: A Prospective Observational Study

Istinye University1 site in 1 country100 target enrollmentStarted: April 10, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
100
Locations
1
Primary Endpoint
Quality of Recovery-15 (QoR-15) Total Score

Overview

Brief Summary

This prospective observational study evaluates the association between postoperative analgesic approaches and recovery outcomes in patients undergoing elective total thyroidectomy. Patients will be followed under routine clinical care without intervention or randomization.

The primary outcome is the Quality of Recovery-15 (QoR-15) score at 24 hours. Secondary outcomes include swallowing pain, resting pain, opioid consumption, postoperative nausea and vomiting, and additional analgesic requirement.

Study Design

Study Type
Observational
Observational Model
Case Control
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to 65 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patients aged 18-75 years
  • ASA physical status classification I-III
  • Patients scheduled for elective bilateral total thyroidectomy
  • Patients undergoing surgery under general anesthesia
  • Individuals able to read and understand Turkish and cognitively capable of completing the QoR-15 questionnaire
  • Patients providing written informed consent to participate in the study

Exclusion Criteria

  • Chronic opioid use (≥3 months of regular opioid use)
  • Presence of chronic pain syndrome
  • Psychiatric illness or cognitive impairment
  • History of neurological disease (stroke, dementia, Parkinson's disease, etc.)
  • Known allergy to local anesthetic agents
  • Previous surgical interventions in the cervical region (including revision thyroid surgery)
  • Planned extended surgery with concomitant neck dissection
  • Substernal/retrosternal goiter cases (with potential need for sternotomy or additional procedures)
  • Emergency surgical procedures
  • Patients with ASA physical status IV or higher

Arms & Interventions

Cervical Plexus Block Group

Patients who receive bilateral intermediate cervical plexus block as part of routine clinical practice, based on the attending anesthesiologist's decision.

No Block Group

Patients who do not receive cervical plexus block and are managed with standard postoperative analgesia according to routine clinical practice.

Intervention: Cervical Plexus Block (Other)

Outcomes

Primary Outcomes

Quality of Recovery-15 (QoR-15) Total Score

Time Frame: 24 hours postoperatively

Quality of recovery will be assessed using the QoR-15 questionnaire. The total score ranges from 0 to 150, with higher scores indicating better recovery. The outcome will be compared between patients who received cervical plexus block and those who did not.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

İlke Dolgun

Assoc.Prof

Istinye University

Study Sites (1)

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