The Effect of Bilateral Uterine Artery Ligation After Intrapartum or Postpartum Hemorrhage on Ovarian Reserve Markers and Pregnancy Outcome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Ovarian reserve by anti-mullerian hormone
研究概览
简要总结
The aim of this study is to assess the possible negative effects of uterine artery ligation on ovarian reserve markers and subsequent pregnancy outcomes
详细描述
One of the most common surgical methods for preserving fertility is uterine artery ligation. It is simple to do and effective at reducing Postpartum hemorrhage after delivery . Additionally, it is rather safe and permits future childbearing for the patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •120 females aged from 20 to 35 years old
- •with Postpartum hemorrhage or intrapartum hemorrhage after cesarean section
- •did not respond to medical therapy
- •performed successful bilateral uterine artery ligation for hemorrhage management.
排除标准
- •The presence of male factor or tubal factor.
- •Hypertension, autoimmune disease, morbid obesity, absence of lactation diabetes millets, vascular disease, smoking or the use of alcohol.
- •The presence of additional surgery or medical disease.
- •Detection of a uterine anomaly, history of intrauterine growth restriction in previous pregnancies.
- •Usage of a hormonal therapy through the research.
结局指标
主要结局
Ovarian reserve by anti-mullerian hormone
时间窗: 24 months after bilateral uterine artery ligation.
Anti-mullerian hormone (AMH) level will be determined using a two-sided immunoassay that will be enzymatically amplified (ELISA). AMH was recorded at 6, 12 and 24 months after bilateral uterine artery ligation.
次要结局
- Percent of subsequent pregnancy cases(24 months after bilateral uterine artery ligation.)
- Ovarian reserve by antral follicle counts(24 months after bilateral uterine artery ligation.)
- Ovarian reserve by follicle stimulating hormone(24 months after bilateral uterine artery ligation.)
研究者
Ahmed Ossman
Assistant Professor of Obstetrics and Gynecology Department Tanta, Faculty of Medicine, Tanta University, Tanta, Egypt.
Tanta University