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Clinical Trials/NCT04518176
NCT04518176
Unknown
Not Applicable

Clinical Outcomes of Bilateral Uterine Artery Ligation During the Cesarean Delivery of Twins: A Randomized Controlled Trial

Aswan University Hospital1 site in 1 country400 target enrollmentSeptember 1, 2020

Overview

Phase
Not Applicable
Intervention
bilateral uterine artery ligation
Conditions
Cesarean Section Complications
Sponsor
Aswan University Hospital
Enrollment
400
Locations
1
Primary Endpoint
mean Blood loss after placental separation
Last Updated
5 years ago

Overview

Brief Summary

Objective to assess the effectiveness of prophylactic bilateral uterine artery ligation (BUAL) in reducing the incidence of postpartum hemorrhage during cesarean delivery among women with twin pregnancy

Detailed Description

A randomized clinical trial at Aswan University Maternity Hospital, Egypt. Women with twin pregnancy undergoing scheduled or emergency cesarean were randomized into two groups. In the BUAL group, women underwent BUAL before placental delivery; in the control group, women had cesarean delivery without BUAL. The primary outcome was the estimated blood loss during a cesarean

Registry
clinicaltrials.gov
Start Date
September 1, 2020
End Date
August 31, 2022
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Aswan University Hospital
Responsible Party
Principal Investigator
Principal Investigator

hany farouk

A Professor

Aswan University Hospital

Eligibility Criteria

Inclusion Criteria

  • women undergoing cesarean section
  • twin pregnancy

Exclusion Criteria

  • Placenta previa.
  • Ante-partum hemorrhage.
  • patient refuse to participate

Arms & Interventions

study group

patients with twin pregnancy undergoing cesarean section underwent bilateral uterine artery ligation and received oxytocin.

Intervention: bilateral uterine artery ligation

study group

patients with twin pregnancy undergoing cesarean section underwent bilateral uterine artery ligation and received oxytocin.

Intervention: Oxytocin

control group

patients with twin pregnancy undergoing cesarean section received oxytocin only.

Intervention: Oxytocin

Outcomes

Primary Outcomes

mean Blood loss after placental separation

Time Frame: 30 minutes

by using weight of soaked towels (weight of soaked towel - weight of dry towel) and amount of blood in suction set

Secondary Outcomes

  • Number of Participants with postpartum hemorrhage(12 hours)
  • The number of participant needed for blood transfusion(24 hours)

Study Sites (1)

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