Detecting local recurrent prostate cancer: MRI:patterns of post-prostatectomy recurrence and of its response to salvege radiotherapy using Enhanced and Dynamic Contrast Enhanced (DCE) MRI

• Conditions: C61; Malignant neoplasm of prostate

• Registration Number: DRKS00003469
• Lead Sponsor: niversitätsklinikum Freiburg, Klinik für Strahlenheilkunde

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2011-06-30
• Study Start: 2012-11-21
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: Male
• Target Recruitment: 33

Inclusion Criteria

Patients with a history of prostate carcinoma Prostatavesikolektomie because of a biochemical (PSA) recurrence (definition of PSA recurrence: three consecutive rising PSA values ??above the nadir,> 3 months after surgery)
- Have received no anti-hormonal therapy prior to radiotherapy
- MRI scan prior to initiation of radiotherapy
- PSA follow-up of at least 1 year after the end of radiotherapy

Exclusion Criteria

Clinical and imaging suspicion of lymph node metastases or distant metastases before initiation of radiation therapy to the pelvis

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sensitivity, specificity and accuracy of DCE-MRI without endorectal coil in the detection of local recurrent PC at very low PSA levels. <br>

Secondary Outcome Measures

Name	Time	Method
Correlation of tumor size to pre-RT PSA-level.