Comparative study of Bronchoalveolar Lavage and Tracheal Aspirate in the diagnosis and treatment of Ventilator-Associated Pneumonia

Faculdade de Medicina da Universidade Federal de Minas Gerais0 sitesNovember 25, 2014

Overview

No summary available.

Registry

who.int

Start Date

November 25, 2014

End Date

TBD

Last Updated

2 years ago

Study Type

Intervention

Sponsor

Faculdade de Medicina da Universidade Federal de Minas Gerais

•The patients under mechanical ventilation for at least 48 h who presented with new or progressive pulmonary infiltrates on X\-rays plus at least two criteria among fever \> 38°C, purulent tracheal secretions, and leukocytos greater than 10,000 cells/mm3 or leukopenia of 4,000 cells/mm3, were screened for enrollment.These patients were randomized to undergo BAL (BAL group \- 1\) or EA (EA group \- 2\).
•Both BAL fluid (BALF) and EA samples were quantitaively cultured. The patients whose cultures were positive with more than 10\.000 CFU/mL in BALF cultures and with more than 100\.000 CFU/mL in quantitatively endotracheal aspirate cultures (QEACs)— were included in the

•The exclusion criteria were a diagnosis of AIDS and inappropriate
•respiratory samples (\> 10 squamous cells in the lower field magnification in EA
•smears or \> 1% bronchial cells in BALF smears). cases with BAL fluid with more than 1% of bronchial cells.