The Effect of Gallstone Characteristics for the Severity of Acute Gallstone Pancreatitis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 301
- 试验地点
- 1
- 主要终点
- Number of severity of GSP patients
研究概览
简要总结
The purpose of this study was to determine the effect of gallstone characteristics for the severity of acute gallstone pancreatitis (GSP)
详细描述
The timing of cholecystectomy is closely related to the severity of acute gallstone pancreatitis (GSP). The effect of gallstone characteristics (including stone size, number, etc.) for the severity of GSP are currently unknown.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute gallstone pancreatitis (GSP) patients.
排除标准
- •Pancreatitis with bile duct stones, trauma, drugs, and surgery;
- •Recurrent gallstone pancreatitis;
- •Combined with other malignant tumors, such as liver cancer, cholangiocarcinoma, pancreatic cancer, gastric cancer, Hematologic tumor, and lymphoma;
- •Previous hepatobiliary and pancreatic surgery, Organ transplantation;
- •Intestinal obstruction or other obstructive diseases;
- •Chronic pancreatitis or pancreatic duct stones;
- •Thrombotic disease;
- •Alcoholic pancreatitis and hyperlipidemia pancreatitis.
结局指标
主要结局
Number of severity of GSP patients
时间窗: 1 month
Based on the 2012 Atlanta International Consensus, Mild acute pancreatitis (MAP) is defined as no organ failure and no local or systemic complications. Moderate to severe acute pancreatitis (MSAP) refers to patients with organ failure, local complications, or aggravated complications. Severe acute pancreatitis (SAP) is defined as persistent organ failure for more than 48 hours.
次要结局
- Modified computed tomography severity index (MCTSI) score(1 month)
- Gallstone size(1 month)
- Number of stones(1 month)
研究者
Wenbo Meng
Professor of surgery
Hepatopancreatobiliary Surgery Institute of Gansu Province