Diagnosis of cystic fibrosis fat malabsorption: fat absorption test.

Recruiting

• Conditions: 1. Cystic fibrosis; <br />2. fat malabsorption (NLD: vetmalabsorptie); <br />3. fecal fat balans (NLD: vetbalans); <br />4. pancreatic insuffiency (NLD: pancreasinsufficientie); <br />5. Lipolysis (NLD: lipolyse); <br />6. fat absorption (NLD: vetabsorptie).

• Registration Number: NL-OMON21173
• Lead Sponsor: Investigator initiated

Brief Summary

1. Rings EH, Minich DM, Vonk RJ, Stellaard F, Fetter WP, Verkade HJ. Pediatr Res. 2002 Jan;51(1):57-63. Functional development of fat absorption in term and preterm neonates strongly correlates with ability to absorb long-chain Fatty acids from intestinal lumen;<br> 2. Kalivianakis M, Minich DM, Bijleveld CM, van Aalderen WM, Stellaard F, Laseur M, Vonk RJ, Verkade HJ. Am J Clin Nutr. 1999 Jan;69(1):127-34. Fat malabsorption in cystic fibrosis patients receiving enzyme replacement therapy is due to impaired intestinal uptake of long-chain fatty acids. Bijvelds MJ, Bronsveld I, Havinga R, Sinaasappel M, de Jonge HR, Verkade HJ Am J Physiol Gastrointest Liver Physiol. 2005 Apr;288(4):G646-53. Fat absorption in cystic fibrosis mice is impeded by defective lipolysis and post-lipolytic events

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 35

Inclusion Criteria

1. Cystic fibrosis patients;

2. Age: 2 -18 years;

Exclusion Criteria

1. Cystic fibrosis related liver disease;

2. Pulmonary (non-)infectious exacerbation;

Study & Design

• Study Type: Interventional
• Study Design: Not specified