Adverse Perioperative Events and Eosinophil Count
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 346
- 试验地点
- 1
- 主要终点
- Any adverse respiratory event that occurs at any point of time in the intraoperative and postoperative period will be recorded. An adverse respiratory event will include any or all of the following: bronchospasm, laryngospasm, a fall in SPO2 to less than 95%, cough and stridor.
研究概览
简要总结
I want to study the relationship between eosinophil count and any adverse events that may occur in the perioperative period. The rationale behind this study is that studies have shown a correlation between airway hyperreactivity and increased blood eosinophil count . Airway hyperreactivity in turn can precipitate adverse respiratory events in the perioperative period. The research hypothesis is that there is a positive correlation between blood eosinophil count and adverse perioperative respiratory events. If the results of this study support the research hypothesis then it will aid in our preparedness to deal with such complications and even take preemptive steps to prevent such events in future.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 3.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of either sex, in the age group of 3 years and above, ASA physical status I or II ,posted for elective surgery, who require general anaesthesia and endotracheal intubation.
排除标准
- •Age less than 3 years,patients cardiac disease, upper respiratory tract infection within the last 2 weeks, difficult airway requiring more than 3 intubation attempts, surgeries involving airway, absolute eosinophil count >1000mm3.
结局指标
主要结局
Any adverse respiratory event that occurs at any point of time in the intraoperative and postoperative period will be recorded. An adverse respiratory event will include any or all of the following: bronchospasm, laryngospasm, a fall in SPO2 to less than 95%, cough and stridor.
时间窗: From the time of induction of anaesthesia to 24 hours post operatively
次要结局
- Any other adverse event that occurs at any point of time in the intraoperative and postoperative period will be recorded.(From the time of induction of anaesthesia to 24 hours post operatively)