Eosinophilia in surgical patients and its impact on perioperative management
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- To identify trends in our anaesthesia practice microvascular surgeries
研究概览
简要总结
We found that the incidence of eosinophilia is 9% in our study population. However it was not associated with increased incidence of perioperative complications like bronchospasm, drug reaction, haemodyanamic instability or anaphylaxis.
of 319 patients with preoperative eosinophilia, postoperative eosinophil count was available in 149 patients. Of these only 20 patients had eosinophilia in immediate postoperative period (13.4%). Of 137 patients who had mild eosinophilia in preoperative period only 8 patients showed eosinophilia immediately after surgery (5.8%). Of 12 patients with hypereosinophilia in preoperative period all 12(100%) showed persistent eosinophilia postoperatively.
Thus our study shows that in cancer patients the eosinophilia is most of the time related to the pathogenesis of the cancer and not a separate disease and could be safely given anaesthesia.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 1.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Charts of all patients undergoing surgery in major operation theatres over a period of 1 year.
排除标准
- •Emergency surgeries.
结局指标
主要结局
To identify trends in our anaesthesia practice microvascular surgeries
时间窗: pre-operative assessment, intra-operative management and post-operative outcomes
To identify potential areas for improvement
时间窗: pre-operative assessment, intra-operative management and post-operative outcomes
次要结局
- To identify specific factors associated with intra- and post-operative complications(pre-operative assessment, intra-operative management and post-operative outcomes)