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Randomized controlled trial of desflurane vs. sevoflurane in pediatric liver transplant patients

Not Applicable
Conditions
Pediatric patients who are scheduled for living donor liver transplantation
Registration Number
JPRN-UMIN000022811
Lead Sponsor
ational Center for Child Health and Development
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Sex
All
Target Recruitment
65
Inclusion Criteria

Not provided

Exclusion Criteria

1) preoperative ICU management; 2) other organ complications caused by diseases other than the present liver illness; 3) allergy to either/both of inhalation anesthetic(s) or halogenated agents; 4) past history of malignant hyperthermia or family history of malignant hyperthermia; 5) metabolic disease; 6) acute liver failure; 7) pulmonary hypertension; 8) respiratory tract symptoms within 2 weeks before surgery; 9) asthma; 10) any cases inappropriate for the trial judged by surgeons or anesthesiologists in charge

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Ratio of operating room extubation after pediatric living donor liver transplantation
Secondary Outcome Measures
NameTimeMethod
1) Length of postoperative intubation 2) Length of Intensive care unit stay 3) Perioperative blood examination 4) Perioperative vital sign change 5) Perioperative infusion therapy volume 6) Perioperative urine output change 7) Ratio of postoperaitve infection 8) Ratio of postoperative rejection
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