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A Clinical Trial Comparing Two Anaesthesia techniques, for physiological changes in patients undergoing Hyperthermic Intraperitoneal Chemotherapy.

Not Applicable
Conditions
Health Condition 1: null- Abdominal malignancy with peritoneal carcinomatosis
Registration Number
CTRI/2017/11/010520
Lead Sponsor
All India Institute of Medical Sciences AIIMS
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Closed to Recruitment of Participants
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Patients classified as ASA I, II or III according to the American Society of Anesthesiologists

2.Scheduled to undergo CRS+HIPEC procedure at Dr. BRAIRCH, AIIMS, New Delhi

Exclusion Criteria

1.Contraindications to epidural block or propofol, desflurane, fentanyl, or morphine.

2.Patients with renal or hepatic disorders

3.Patient suffering from coagulopathy or receiving any anticoagulants.

4.Left Ventricular Ejection Fraction < 45%, RWMA, Arrhythmia, Conduction defect

5.Patient with BMI>=35kg/m2.

6.Hypersensitivity to local anesthetics

7.Thyrotoxicosis

8.Mental retardation

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To Compare the effect of Two Anaesthetic techniques on Hemodynamic Changes during HIPEC surgery.Timepoint: Several Time Points
Secondary Outcome Measures
NameTimeMethod
To study Perioperative systemic effects in the two groups and study the Perioperative changes in Inflammatory markers <br/ ><br>Timepoint: perioperative period
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