MPV and NLR as Predictors of SBP Diagnosis

Completed

• Conditions: Spontaneous Bacterial Peritonitis

• Registration Number: NCT04775420
• Lead Sponsor: Sohag University

Brief Summary

The aim of the study is to investigate the clinical utility of mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) as diagnostic markers for spontaneous bacterial peritonitis (SBP).

Detailed Description

Not available

Study Timeline

• Study Start: 2020-04-01
• Study First Submitted: 2021-02-25
• Study First Submitted QC: 2021-02-26
• Study First Posted: 2021-03-01
• Primary Completion: 2022-04-30
• Study Completion: 2022-04-30
• Status Verified: 2023-01
• Last Update Submitted: 2023-01-20
• Last Update Posted: 2023-01-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 332

Inclusion Criteria

• Decompensated liver cirrhosis ascetic patients.

Exclusion Criteria

• Immunocompromised patients.
• Patients who had received antibiotics before hospital admission.
• Patients on anticoagulant medications, NSAIDs, or oral contraceptive drugs.
• Patients with heart failure, diabetes mellitus, hypertension, hyperlipidemia, peripheral vascular disease, hematological disorders, and neoplastic disorders and patients with clinically overt hypothyroidism or hyperthyroidism or with clinically and laboratory-evident autoimmune diseases.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The utility of MPV as non-invasive predictor of SBP	1 year	It will be measured from CBC
The utility of NLR as non-invasive predictor of SBP	1 year	It will be measured from CBC

Trial Locations

Locations (1)

Sohag Faculty of Medicine; 🇪🇬 Sohag, Egypt