Metabolome analysis in association with the effects of Inchinkoto, a herbal medicine.
Not Applicable
- Conditions
- The patients who undergo percutaneous transhepatic biliary drainage (PTBD) or endoscopic nasobiliary drainage (ENBD) due to biliary obstruction. Among the, patients who were included the study "The association between the intestinal microenvironment and choleretic effects of Inchinkoto. (UMIN 000013250) with blood and bile sampling.
- Registration Number
- JPRN-UMIN000020274
- Lead Sponsor
- agoya University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 46
Inclusion Criteria
Not provided
Exclusion Criteria
1. Patients who do not agree to participate this study. 2. Patients who are not eligible to participate this study (determined by chief or associate doctors who are responsible to perform this study. 3. Patients who are allergic to Inchinkoto. 4. Patients who are taking choleretic drugs such as ulsodeoxycholic acid.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Alternation of metabolome after an oral intake of Inchinkoto.
- Secondary Outcome Measures
Name Time Method The association between the serum concentrations of genipin, geniposide, and 6,7-dimetylesculetin and the biliary concentrations of total bilirubin, direct bilirubin, and bile acid.