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To compare drugs having more pain relieving action by adding them to primary drug and giving via abdominal block in patients undergoing lower abdominal surgeries

Phase 3
Conditions
Health Condition 1: R52- Pain, unspecifiedHealth Condition 2: O00-O9A- Pregnancy, childbirth and the puerperium
Registration Number
CTRI/2024/06/069447
Lead Sponsor
Jekha Mary Babu
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1) ASA grade I or II fit patients, 2)Ages between 18 and 65 years, 3) Patients undergoing lower abdominal surgeries under spinal anaesthesia, 4) Hemodynamically stable patients with all routine investigations within normal limits without any other co-morbidities, 5)Patients who are not on any cardiac related drugs, 6) Availability of written informed consent from concerned patient.

Exclusion Criteria

1)Patients not willing to participate in this study, 2)Patients with ASA physical status III and above physical status, 3)Patients less than 18 years and above 65 years of age, 4)Patients with uncontrolled systemic disorders like neurological, cardiac, metabolic, renal, pulmonary disorders, hepatic disease with coagulation abnormalities etc, 5)Patients on calcium channel blocker, 6)Patients having local infection at the site where needle for block was to be inserted, 7)Patients with contraindication for spinal anaesthesia, 8)Patients with bleeding or coagulation disorders, 9)Patients with known allergies to the study drugs, 10)Patients with weight less than 40 kgs and height less than 140 cms

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
A comparative study of magnesium sulphate versus dexamethasone as an adjuvant to bupivacaine in ultrasound-guided transversus abdominis plane block in patient undergoing lower abdominal surgeriesTimepoint: After administration of the block, pain scores will be assessed in both the groups in less than 5 minutes after giving block, after 2 hours, after 4 hours, after 6 hours, after 12 hours, after 16 hours, after 20 hours, and after 24 hours will be assessed
Secondary Outcome Measures
NameTimeMethod
A comparative study of magnesium sulphate & dexamethasone as an adjuvant to bupivacaine in ultrasound-guided transversus abdominis plane block in patient undergoing lower abdominal surgeriesTimepoint: Duration of analgesia will be assessed post giving block after surgery & time to rescue analgesia will be assessed
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