High Frequency Chest Wall Oscillation in Hospital Management of Asthmatic Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 43
- 试验地点
- 4
- 主要终点
- The Primary Endpoint Will be Time to Readiness for Discharge.
研究概览
简要总结
To determine whether or not high frequency chest wall oscillation (in the form of the VestTM) is superior to regular asthma therapy in the management of children hospitalized with moderate to severe asthma.
详细描述
A historically controlled pilot study was conducted in pediatric patients 18 months to 18 years of age hospitalized with a diagnosis of asthma or reactive airway disease and admitted to the pediatric intensive care unit. Upon receiving informed consent, patients were treated with HFCWO therapy via the VEST. The primary endpoint was time to readiness for discharge, lack of need for continued supportive care (e.g., intravenous fluid or oxygen), and bronchodilator treatments spaced at least four hours apart.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Months 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Any pediatric patient between the ages of 18 months and 18 years admitted to Winthrop University Hospital's pediatric floor or intensive care unit with a diagnosis of asthma or reactive airway disease
排除标准
- •Patients with chronic, comorbid respiratory conditions (e.g., cerebral palsy, cystic fibrosis)
- •Those who regularly use HFCWO
- •Any patient exhibiting an absolute contraindication to HFCWO therapy
- •Absolute contraindications to using HFCWO include head and neck injury prior to stabilization, and active hemorrhage with hemodynamic instability
研究组 & 干预措施
Vest Arm
HFCWO treatments 2-3 times daily 15 minutes per treatment via the VEST
干预措施: VEST (Device)
Control
Historical control for PICU asthma patients
结局指标
主要结局
The Primary Endpoint Will be Time to Readiness for Discharge.
时间窗: 30 days
Days in the hospital prior to patient being clinically ready to discharge
次要结局
- Secondary Endpoint Total Hospital Length of Stay(30 Days)