Efficacy and safety of high frequency chest wall oscillation in paediatric patients with neuromuscular disorders

Not Applicable

• Conditions: euromuscular disease; Impaired airway clearance; Neuromuscular disease; Respiratory - Other respiratory disorders / diseases; Neurological - Neurodegenerative diseases; Musculoskeletal - Other muscular and skeletal disorders

• Registration Number: ACTRN12620000528954
• Lead Sponsor: Queensland Children's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-04-30
• Last Update Posted: 4 May 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 7

Inclusion Criteria

Children aged up to 18 admitted to QCH PICU with the following:
•Diagnosed neuromuscular disorder
•Requiring chest physiotherapy for airway clearance
•Using non-invasive ventilation, either for respiratory support, sleep, or with airway clearance and requiring an escalation of pressures during chest physiotherapy
•In the acute phase of a respiratory exacerbation requiring intensive care admission
•Parent or guardian able and willing to provide informed consent

Exclusion Criteria

•Children with unclear or unconfirmed neuromuscular diagnosis
•Children not requiring physiotherapy for airway clearance
•Children contraindicated for non-invasive ventilation including significant and undrained pneumothorax, chest trauma, facial trauma or facial burns, severe cardiovascular compromise
•Children contraindicated for treatment with HFCWO including open abdominal wounds, unstable spinal injuries, rib fractures, severe haemodynamic instability
•Skin conditions which would preclude the use of electrodes as used in EIT or ECG monitoring, or application of gel for ultrasound imaging

Study & Design

• Study Type: Observational
• Study Design: Not specified