Evaluation of the effects of calcium supplementation alone and with calcitriol in preventing the symptoms of hypocalcemia following total or near total thyroidectomy
- Conditions
- Symptomatic hypocalcemia after total or near-total thyroidectomy.Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified
- Registration Number
- IRCT20210513051285N1
- Lead Sponsor
- Vice Chancellor for Research and Technology, Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
In this study, patients who are candidates for surgery and removal of both thyroid lobes total or near-total due to multinodular goiter or thyroid cancer will be selected.
Patients with preoperative hypocalcemia
Patients with intraoperative parathyroid injury (mentioned by the surgeon , autograft and ischemic symptoms),
Presence of parathyroid adenoma before or after surgery or any underlying disease that impairs parathyroid hormone, vitamin D, calcium, and albumin levels (such as chronic kidney disease or known diseases of malabsorption and indigestion) ,
Patients who have undergone extensive cervical lymphadenectomy during thyroidectomy, Patients with hypercalcemia and hypercalciuria, patients with calcium kidney stones, ventricular fibrillation, digoxin toxicity, sarcoidosis and Vit D poisoning.
Patient dissatisfaction with participating in this study
The presence of a previous major procedure (such as total laryngectomy and parathyroidectomy), receiving prophylactic medication for osteoporosis (including calcium and vitamin D supplementation).
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum calcium level. Timepoint: Before surgery, 6 to 12 hours after surgery, 18 to 24 hours after surgery, 48 to 72 hours after surgery, next in case of recurrence of hypocalcemia and discharge time. Method of measurement: Based on laboratory tests.
- Secondary Outcome Measures
Name Time Method Clinical signs of calcium deficiency. Timepoint: Every 2 hours. Method of measurement: History and examination.