Effect of flaxseed oil supplementation on severity of depression and serum level of BDNF- a in depressed women: a randomized, double blind clinical trial
Not Applicable
Recruiting
- Conditions
- Depressive disorder.Major depressive disorder, single episode
- Registration Number
- IRCT20130903014551N3
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
Ages 18 to 45 years old
Having Depression confirmed by a Psychiatrist according to DSM-IV criteria and being treated with antidepressant medications
Willingness to cooperate in the project
Exclusion Criteria
Having cardiovascular disease and hypertension
Having kidney, liver, cancer, diabetes and inflammatory diseases
Having addiction and taking any drugs, tobacco or alcohol
Taking any multivitamin and omega-3 supplements 3 months before the study
Having cysts in the breast and ovary or having family history of cysts
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of depression. Timepoint: Before and after intervention. Method of measurement: Beck questionnaire.;Serum level of BDNF. Timepoint: Before and after intervention. Method of measurement: ELISA method.
- Secondary Outcome Measures
Name Time Method Physical activity. Timepoint: At the beginning and end of the intervention. Method of measurement: Physical activity record questionnaire.;Dietary intake. Timepoint: At the beginning the intervention, In the fifth week and end of the intervention. Method of measurement: Two day food record.