Recurrence of Dupuytren*s Disease after treatment with Collagenase Clostridium Histolyticum in the thumb.
Completed
- Conditions
- Dupuytren's Diseasefibromatosis palmaris10043237
- Registration Number
- NL-OMON42619
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 12
Inclusion Criteria
12 subjects who had CCH treatment in 14 thumbs during previous study.
Exclusion Criteria
Subjects who had new treatment of the thumb or first webspace since their treatment with CCH will be excluded
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Contractures are measured with a goniometer. Baseline is the measurement of<br /><br>ROM in degrees of the extension deficit as measured 30 days after the<br /><br>injection with CCH . We measure the mean increase of contracture and the<br /><br>deviation.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable</p><br>
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie Dupuytren's Disease recurrence after collagenase Clostridium histolyticum treatment in the thumb?
How does collagenase Clostridrum histolyticum compare to needle aponeurotomy in managing thumb contractures in Dupuytren's Disease?
Are there specific biomarkers that predict recurrence risk in Dupuytren's Disease patients treated with collagenase Clostridium histolyticum for thumb contractures?
What are the long-term adverse event profiles of collagenase Clostridium histolyticum in Dupuytren's Disease treatment for the thumb?
What are the potential combination therapies with collagenase Clostridium histolyticum for preventing Dupuytren's Disease recurrence in the thumb?