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Myocardial Infarction in the Young: A Retrospective Clinical Registry Study

Not Applicable
Recruiting
Conditions
Myocardial Infarction
Cardiovascular - Coronary heart disease
Registration Number
ACTRN12623001097639
Lead Sponsor
Western Sydney Local Health District
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
1000
Inclusion Criteria

1. Patients aged =>18 years and <=50 years old with acute myocardial infarction (MI)
2. Patients aged >50 years and with acute myocardial infarction (MI) (control group)
2. Type 1 and Type 2 MI are both included, with MI defined according to the 4th universal definition: clinical evidence of acute myocardial ischaemia and detection of a rise and/or fall of cTroponin values with at least 1 value above the 99th percentile upper reference limit and, at least one of the following:
a. Symptoms of myocardial ischaemia;
b. New ischaemic ECG changes;
c. Development of pathological Q waves;
d. Imaging evidence of new loss of viable myocardium or new regional wall motion abnormality in a pattern consistent with an ischaemic aetiology;
e. Identification of a coronary thrombus by angiography or autopsy

3. Participants must have undergone coronary angiography

Exclusion Criteria

# Rise in cardiac biomarkers and/or ECG changes due to a clear non-coronary artery pathology e.g. myocarditis, acute arrhythmia, cardiomyopathy, acute pulmonary embolism (PE), stroke, recent cardiac surgery (these can all cause ischaemic changes on the ECG and/or troponin rises)

#Patients with presumed MI who die before the diagnosis has been confirmed by troponin values or coronary angiography (Type 3 MI)

#Percutaneous coronary intervention (PCI)-related MI (Type 4 MI)

#Coronary artery bypass grafting (CABG)-related MI (Type 5 MI)

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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