Evaluation of the effect of colchicine on the frequency of ventricular and supraventricular arrhythmias
Phase 3
- Conditions
- Ventricular arrhythmias.Re-entry ventricular arrhythmiaI47.0
- Registration Number
- IRCT20120520009801N13
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 134
Inclusion Criteria
Age more than 18 years
Having an implantable cardioverter-defibrillator for more than 3 months before starting participation in the clinical trial
Obtaining the patient's informed consent
Exclusion Criteria
Taking the drug Colchicine before
Pregnancy or suspected pregnancy
Active inflammation or infection
Suffering from autoimmune diseases and malignancies
Taking class I and III antiarrhythmic drugs
Performing major surgeries
Treatment with corticosteroids or other immunosuppressive drugs
Moderate to severe kidney dysfunction (GFR < 30 ml/min/1.73m2)
Significant impairment of liver function (Child-Pugh class B or C)
Concomitant use of strong Cyp3A4 inhibitors
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method