Effect of Colchicine in treatment of chronic urticaria

Phase 3

Recruiting

• Conditions: Positive Autoantibody Chronic Urticaria.; Idiopathic urticaria; L50.1

• Registration Number: IRCT20200406046967N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 18 May 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Patients with chronic urticaria in the age range of 20 to 70 years

Exclusion Criteria

pregnant and lactating females
Patients with Physical Urticaria and Vasculitis Urticaria
Patients with Colchicine-induced drug side effects

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage of people with chronic urticaria who have autoimmune thyroiditis. Timepoint: Measurement of thyroid autoantibodies at the beginning of the study (before the intervention) and 3 months after taking colchicine. Method of measurement: Peripheral blood sample.

Secondary Outcome Measures

Name	Time	Method
The urticaria score in the Chronic Urticaria Quality of Life questionnaire. Timepoint: Comparison of the average total score of the Chronic Urticaria Quality of Life questionnaire in the study groups at the beginning of the study and 3 months after taking colchicine. Method of measurement: Chronic Urticaria Quality of Life questionnaire.; The urticaria score in the Urticaria Activity Score 7 questionnaire. Timepoint: Comparison of the average total score of the Urticaria Activity Score 7 questionnaire in the study groups at the beginning of the study and 3 months after taking colchicine. Method of measurement: Urticaria Activity Score 7 questionnaire.