The Value of F-18-fluorodeoxyglucose positron emission tomography for detection of metastatic infectious foci complicating Gram-positive bacteremia.
Completed
- Conditions
- FDG-PETinfectionbacteremiametastatic infectionStaphylococcus aureusStreptococcus speciesEnterococcus speciesendocarditis
- Registration Number
- NL-OMON24175
- Lead Sponsor
- Prof. dr. W.J.G. OyenDepartment of Nuclear MedicineRadboud University Nijmegen Medical CentreP.O. Box 9101, 6500 HB NijmegenThe NetherlandsT: 31 (0)24 3614048Prof dr. B.J. KullbergDepartment of Internal MedicineRadboud University Nijmegen Medical CentreP.O. Box 9101, 6500 HB NijmegenThe NetherlandsT: 31 (0)24 3614763
- Brief Summary
Cuijpers et al, Complicating infectious foci in patients with Staphylococcus aureus or Streptococcus species bacteraemia. Eur J Clin Microbiol Infect Dis 2007:105-113;<br> - Bleeker-Rovers et al, 18F-FDG PET in detecting metastatic infectious disease. J.Nucl Med 2005:2014-2019.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 115
Inclusion Criteria
1. All patients with blood cultures containing one of the following microorganisms:
a. S. aureus;
Exclusion Criteria
1. Age less than 18 years;
2. Polymicrobial infection;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Relapse rate of infection.
- Secondary Outcome Measures
Name Time Method 1. Attributable mortality;<br /><br>2. Mortality after relapse;<br /><br>3. Duration of first admission;<br /><br>4. Duration of antibiotic treatment;<br /><br>5. Number of diagnostic procedures performed to confirm metastatic foci, duration of admission due to relapse;<br /><br>6. Associated costs.