Muscle Oxygenation in Treadmill and Cycle Ergometer Exercise

Not Applicable

Not yet recruiting

• Conditions: Treadmill; Muscle Oxygenation
• Interventions: Other: Questionnare; Device: Moxy Muscle Oxygen Monitor

• Registration Number: NCT05655559
• Lead Sponsor: Saglik Bilimleri Universitesi

Brief Summary

The study will be conducted on healthy young adults. Hemodynamic effects such as heart rate, blood pressure, oxygen saturation (SpO2), including muscle oxygenation, will be compared in treadmill and bicycle exercises.

Detailed Description

In recent studies, sensor systems that measure the oxygen level in muscle tissue at the microvascular level have been developed. These devices working with Near Infrared Spectroscopy (NIRS, 630-850 nm) method; It provides measurements of muscle oxygenation level at rest and during exercise. It is known that significant changes in vastus lateralis oxygenation levels measured by the NIRS method are associated with various factors such as exercise intensity, exercise profile and training. The aim of this study is to measure the oxygenation level of the vastus lateralis muscle during the exercises performed on the treadmill and bicycle ergometer, and thus to reveal the effect of using different ergometers on fatigue and sportive performance.

Muscle oxygen levels will be measured and evaluated before, during and after exertion. In addition, blood pressure (BP), oxygen saturation (SpO2), dyspnea and fatigue parameters will be recorded and evaluated. If undesirable symptoms are observed during our study, the exercise will be terminated. Within the scope of the project, the acute effect will be examined with the measurements made with the Moxy device on the vastus lateralis muscle during the treadmill and bicycle ergonometer.

Study Timeline

• Status Verified: 2022-11
• Study First Submitted: 2022-12-09
• Study First Submitted QC: 2022-12-09
• Last Update Submitted: 2022-12-09
• Study First Posted: 2022-12-19
• Last Update Posted: 2022-12-19
• Study Start: 2022-12-30
• Primary Completion: 2023-03-30
• Study Completion: 2023-05-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• Volunteering to participate in the study
• No known disease
• Be between the ages of 18-25

Exclusion Criteria

• Having cardiopulmonary disease,
• Have had lower extremity muscle or joint injuries
• Having an orthopedic/neurological disorder
• Smoking and alcohol use,
• Have suffered a lower extremity muscle or joint injury,
• Having an orthopedic/neurological disorder,
• Uncontrollable asthma,
• PaO2< 50 mmHg,
• PaCO2> 70mmHg,
• Individuals with a resting systolic blood pressure of 200 mmHg

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Treadmill Group	Questionnare	Hemodynamic effects such as heart rate, blood pressure, oxygen saturation (SpO2), dyspnea and fatigue including muscle oxygenation, will be compared during treadmill exercises.
Treadmill Group	Moxy Muscle Oxygen Monitor	Hemodynamic effects such as heart rate, blood pressure, oxygen saturation (SpO2), dyspnea and fatigue including muscle oxygenation, will be compared during treadmill exercises.
Cycle Group	Questionnare	Hemodynamic effects such as heart rate, blood pressure, oxygen saturation (SpO2), dyspnea and fatigue including muscle oxygenation, will be compared during cycling exercises.
Cycle Group	Moxy Muscle Oxygen Monitor	Hemodynamic effects such as heart rate, blood pressure, oxygen saturation (SpO2), dyspnea and fatigue including muscle oxygenation, will be compared during cycling exercises.

Primary Outcome Measures

Name	Time	Method
Measurement of Muscle Oxygenation	Baseline	Measurement of muscle oxygenation with Moxy Monitor.
Measurement of Patient-Reported Dyspnea and Fatigue	Baseline	Measurement of dyspnea during submaximal exercise with The Modified Borg Dyspnea Scale (MBS).