Non-responders to Antiplatelet Treatment in Acute Ischaemic Stroke)

Completed

• Conditions: Acute Ischemic Stroke
• Interventions: Other: blood sampling for HOTPR-testing

• Registration Number: NCT02607358
• Lead Sponsor: Zealand University Hospital

Brief Summary

Determination of frequency of Clopidigrel- and Acetacylicacid-non-responders (HOTPR) in acute ischemic stroke patients.

Detailed Description

Determination of frequency of Clopidigrel- and Acetacylicacid-non-responders (HOTPR) in acute ischemic stroke patients using the VerifyNow system.

Study Timeline

• Study Start: 2015-01
• Study First Submitted: 2015-11-16
• Study First Submitted QC: 2015-11-17
• Study First Posted: 2015-11-18
• Primary Completion: 2016-08
• Study Completion: 2016-08
• Status Verified: 2016-10
• Last Update Submitted: 2016-10-12
• Last Update Posted: 2016-10-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 496

Inclusion Criteria

• Suspected acute ischemic stroke and loading dose of Clopidogrel or Acetacylicacid

Exclusion Criteria

• Previous treatment with platelet inhibitor
• NOAC or Vitamin K-antagonist treatment
• Final diagnosis other than Ischemoc stroke or Transitoric ischemic attack

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Clopidogrel	blood sampling for HOTPR-testing	Clopidogrel non-responders (HOTPR) Blood sampling for HOTPR-testing
Acetacylicacid	blood sampling for HOTPR-testing	Acetcylicacid non-responders (HOTPR), Blood sampling for HOTPR-testing

Primary Outcome Measures

Name	Time	Method
Responder status	immediately	Platelet reactivity with PRU measurement

Trial Locations

Locations (1)

Neurologisk afdeling; 🇩🇰 Roskilde, Denmark