Analysis of the potency of individual allergens in relation to IgE recognition in patients with cow's milk, peanut or nut allergy.

Completed

• Conditions: food allergy; food hypersensitivity; 10001708

• Registration Number: NL-OMON36035
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 90

Inclusion Criteria

* > 18 years of age
* cow's milk/peanut/nut allergy proven by DBPCFC (or in severe cases by clear history)
* specific IgE cow's milk/peanut/nuts >0.35 kU/L

Exclusion Criteria

* other systemic diseases
* immune-compromised
* systemic treatment with immuno-modulatory drugs

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>* T cell activation: which allergen is the most potent T cell activor?<br /><br>* Basophil activation test: which allergen is the most potent basophil<br /><br>activator?</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>